PSD95結(jié)合蛋白3抗體,Anti-SAPAP3抗體
研究領(lǐng)域 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞類型標(biāo)志物 細(xì)胞膜蛋白
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Cow, Horse,
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 106kDa
細(xì)胞定位 細(xì)胞膜
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SAPAP3
亞 型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
訂購:或(成)客服
英文名稱 SAPAP3
抗體名稱 PSD95結(jié)合蛋白3抗體,Anti-SAPAP3抗體
別 名 PSD95BP3; DLGAP3; PSD 95/SAP90 binding protein 3; SAP90/PSD 95 associated protein 3; DAP3; Discs, large (Drosophila) homolog associated protein 3; Disks large associated protein 3; DLGAP3; SAPAP 3; DLGP3_HUMAN.
濃 度 1mg/1ml
規(guī) 格 0.1ml/0.2ml(100ug/200ug)
公司提供的抗體達(dá)一萬多種,公司擁有Complexin I/復(fù)合素1抗體一抗,二抗,標(biāo)記一抗,標(biāo)記二抗等抗體種類,*價(jià)供應(yīng)。
多克隆抗體制備服務(wù):應(yīng)用保證型抗體制備(ELISA,Western Blot,IHC)和修飾特異性抗體制備(磷酸化,甲基化,乙?;?。
單克隆抗體制備服務(wù):應(yīng)用保證型抗體制備(ELISA,Western Blot,IHC)和修飾特異性抗體制備(磷酸化,甲基化,乙?;?。
抗體純化服務(wù):Protein A/G/L純化,抗原親和純化。
zui終抗體質(zhì)檢:成品抗體或抗血清,必須通過客戶要求的所有驗(yàn)證(ELISA,Western Blot,IHC等)。所有的抗原和抗體驗(yàn)證數(shù)據(jù)提交客戶。
免疫組化的呈色深淺可反映抗原存在的數(shù)量,可作為定性、定位和定量的依據(jù)。
1.陽性細(xì)胞染色分布有三種類型:細(xì)胞漿、細(xì)胞核、細(xì)胞膜表面。大部分抗原見于細(xì)胞漿,可見于整個(gè)胞漿或部分胞漿
2.陽性細(xì)胞分布可分為灶型和彌漫性
3.由于細(xì)胞內(nèi)含抗原量不同,所以染色強(qiáng)度不一。如果細(xì)胞之間染色強(qiáng)度相同,常提示其反應(yīng)為非特異性
4.陽性細(xì)胞染色定位于單個(gè)細(xì)胞,且與陰性細(xì)胞相互交雜分布;而非特異性染色常不限于單個(gè)細(xì)胞,而是累及一片細(xì)胞。
5.切片邊緣、刀痕或褶皺區(qū)域,壞死或擠壓的細(xì)胞區(qū),膠原結(jié)締組織等,常表現(xiàn)為相同的陽性染色強(qiáng)度,不能用于判斷陽性。
產(chǎn)品介紹 Members of the postsynaptic density-95 (PSD-95)/SAP90 family of membrane-associated guanylate kinase (MAGUK) proteins function as multimodular scaffolds that organize protein-signaling complexes at neuronal synapses. SAPAP3 (PSD-95/SAP90-binding protein 3), also known as DLGAP3 (disks large-associated protein 3) or DAP3, is a 979 amino acid protein that belongs to the SAPAP family of PSD-95/SAP90-associated proteins. Localized to the cell junction, as well as to the peripheral membrane and the cell synapse, SAPAP3 is thought to play a role in the organization of neuronal cell signaling and synapses, and may also function as an adaptor protein, possibly linking ion channels with the cytoskeleton.
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