Description: CCL19, also known as MIP-3 beta (Macrophage Inflammatory Protein 3 beta), is a member of the CC- subfamily of chemokines. It is most closely related to CCL21, with which it shares 32% amino acid sequence homology. CCL19 and CCL21 are expressed mainly by stromal cells in the T cell-rich zones of lymph nodes. They are critical mediators of the homeostatic trafficking of naïve T cells and activated dendritic cells into the secondary lymphoid organs. CCL19 and CCL21 also play a role in T cell priming and activation, as well as the recruitment of lymphocytes to inflamed tissue. Both proteins signal via the G protein-coupled receptor, CCR7, which is expressed on T cells and mature dendritic cells. Although CCL19 and CCL21 both exhibit the same affinity for CCR7, only the binding of CCL19 results in the desensitization and internalization of the receptor.
上海經(jīng)科化學(xué)科技有限公司,是一家專(zhuān)注于生命科學(xué)和生物技術(shù)領(lǐng)域的高科技企業(yè),專(zhuān)業(yè)提供分子生物學(xué)、免疫學(xué)、生命科學(xué)基礎(chǔ)研究諸多領(lǐng)域的試劑產(chǎn)品及生物技術(shù)服務(wù)。
公司注重跟蹤世界范圍分子生物學(xué)、細(xì)胞生物學(xué)等生物學(xué)科的發(fā)展前沿,努力將歐美專(zhuān)業(yè)生產(chǎn)廠家的具有*水平的產(chǎn)品*給各類(lèi)研究人員。公司客戶(hù)遍布大學(xué)、研究所、醫(yī)院、衛(wèi)生防疫、商品檢驗(yàn)檢疫、制藥公司、生物技術(shù)公司和食品工業(yè)等單位。
公司目前已與國(guó)外多家*試劑供應(yīng)商建立了*穩(wěn)定的合作關(guān)系,公司目前已經(jīng)成為osenses(澳大利亞)、lifespan(美國(guó))、neuromics(美國(guó))、everest biotech(英國(guó))、anaspec(美國(guó))、biosensis(澳大利亞)、adar(以色列)、prospec(以色列)、biotrend(德國(guó))、randox(英國(guó))、biaffin(德國(guó))、usbio(美國(guó))、innovabiosciences(英國(guó))、gallus(加拿大)、advimmuno(美國(guó))等多家國(guó)外公司的國(guó)內(nèi)*代理和一級(jí)代理。這將進(jìn)一步為中國(guó)科技人員或科技公司提供更多更好的產(chǎn)品, 有些少見(jiàn)的產(chǎn)品*了市場(chǎng)的空白。
公司在重視產(chǎn)品質(zhì)量的同時(shí),也建立了一套集技術(shù)支持、物流、售后服務(wù)等多個(gè)部門(mén)的*的服務(wù)體系,努力把我們方便、快捷、周到的服務(wù)提供給每一個(gè)客戶(hù)。
Also known as: C-C Motif Chemokine 19
RUO: For Research Use Only. Not for use in diagnostic procedures.
- HumanEGFRecombinantProteinCarrie
- Anti-MouseNKG2A/C/EPerCP-eFluor?
- MouseIFNgammaPlatinumELISA(extr
- Anti-MouseCD38PerCP-eFluor?710
- Anti-HumanCD279(PD-1)PE-Cy7
- Anti-CD27FunctionalGradePurified
- Anti-CD27APC
- Anti-MouseCD26PerCP-Cy5.5
- Anti-MouseCD25eFluor?450(Pacifi
- Anti-MouseCD24eFluor?605NC
- CD19PerCP-Cy5.5
- Anti-HumanCD19PEandCD5FITCCockta