DGCR6L抗體,無胸腺癥關(guān)鍵蛋白6樣抗體(迪格奧爾格綜合征)抗體應(yīng)用于WB、IHC、IF、ELISA等實驗中，產(chǎn)品貨期快、質(zhì)量品牌保障，并提供完善的售前、售中、售后服務(wù)！咨詢或在線客服！我們將竭誠為您服務(wù)！公司堅持對產(chǎn)品質(zhì)量作不斷的評估、創(chuàng)新和改善以確保您對我們產(chǎn)品的高度信任！
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DGCR6L抗體,無胸腺癥關(guān)鍵蛋白6樣抗體(迪格奧爾格綜合征)產(chǎn)品介紹 Neural crest cell migration to the third and fourth pharyngeal pouches is a critical step in the structural formation of organs that are affected in DiGeorge syndrome. DGCR6 (DiGeorge syndrome critical region 6) is a nuclear protein that plays a role in neural crest cell migration and is located at the DiGeorge syndrome critical region (DGCR) on chromosome 22. Expressed ubiquitously with highest levels in heart, liver and skeletal muscle, DGCR6 shares high homology with the Drosophila gonadal (gdl) protein and with human Laminin-1, both of which are involved in early tissue development. The gene encoding DGCR6, along with other DGCR genes, is deleted in DiGeorge syndrome; a developmental disorder characterized by improper facial, cardiac and palate formation. Upregulation of DGCR6 is implicated in lung and colon adenocarcinomas, as well as in Burkitt’s lymphoma and lymphocytes transformed by EBV. Due to a duplication of the ancestral DGCR6 locus, there are two functional, highly homologous copies of the DGCR6 gene (designated DGCR6 and DGCR6L) on chromosome 22.
無胸腺癥關(guān)鍵蛋白6樣抗體(迪格奧爾格綜合征)儲存溫度：存在于血清、組織培養(yǎng)上清液或腹水中的抗體在-20℃下能夠*儲存。低溫存放不會損傷抗體活性?？贵w的工作液通常儲存于4℃中。此溫度下，抗體的活性能穩(wěn)定數(shù)月至數(shù)年亦不損失?？贵w溶液不應(yīng)反復凍融，因為反復凍融將導致部分抗體失活并產(chǎn)生不需要的蛋白—蛋白凝聚物?？贵w的凝聚能導致活性喪失。這是由于抗原結(jié)合位點的空間構(gòu)象被破壞，或由于產(chǎn)生的不溶物被離心或過濾而除去。冷凝蛋白類的抗體不能存放于4℃。因為在4℃下此類抗體會發(fā)生沉淀。一些鼠源性IgG3亞類的抗體有此特性。如果抗體在4℃下發(fā)生沉淀，就應(yīng)該存放于室溫下的疊氮鈉溶液中。
保存條件：低溫
運輸：4度，或干冰。
公司抗體具有高純度、高效價、高特異性的特點，僅用于科學研究，不可用于臨床診斷及藥物治療，可以應(yīng)用于多種實驗。

英文名稱 DGCR6L
抗體名稱 DGCR6L抗體,無胸腺癥關(guān)鍵蛋白6樣抗體(迪格奧爾格綜合征)
別    名 DGC6L_HUMAN; DGCR6L; DiGeorge syndrome critical region 6-like protein; Protein DGCR6L.  
研究領(lǐng)域 腫瘤  細胞生物  免疫學  神經(jīng)生物學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Cow, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
細胞定位 細胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DGCR6L
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

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